Publication
2020
Sugeno A, Piao W, Yamazaki M, Takahashi K, Arikawa K, Matsunaga H, Hosokawa
M, Tominaga D, Goshima Y, Takeyama H, Ohshima T. Cortical transcriptome
analysis after spinal cord injury reveals new insights on the regeneration
mechanism of CNS upon inhibition of CRMP2 phosphorylation. Neural Regeneration Research 16(7):1258-1265. DOI: 10.4103/1673-5374.301035
Togashi K, Hasegawa M, Nagai J, Kotaka K, Yazawa A, Takahashi M, Masukawa
D, Goshima Y, Hensley K, Ohshima T. Lanthionine ketimine ester improves
outcome in an MPTP-induced mouse model of Parkinson’s disease via suppressions
of CRMP2 phosphorylation and microglial activation. J Neurol Sci 413:116802. DOI: 10.1016/j.jns.2020.116802
O. Schanz, R. Chijiiwa, S. C. Cengiz, Y. Majlesain, H. Weighardt, H. Takeyama
and I. Förster, Dietary AhR Ligands Regulate AhRR Expression in Intestinal
Immune Cells and Intestinal Microbiota Composition, Int. J. Mol. Sci, 21(9):3189, 2020, doi:10.3390/ijms21093189
M. Yamazaki, M. Hosokawa, K. Arikawa, K. Takahashi, C. Sakanashi, T. Yoda, H. Matsunaga and H. Takeyama, Effective microtissue RNA extraction coupled with Smart-seq2 for reproducible and robust spatial transcriptome analysis, Sci. Rep., 10(1): 1-8, 2020, doi:10.1038/s41598-020-63495-6
M. Yumoto, N. Hemmi, N. Sato, Y. Kawashima, K. Arikawa, K. Ide, M. Hosokawa,
M. Seo and H. Takeyama, Evaluation of the effects of cell-dispensing using
an inkjet-based bioprinter on cell integrity by RNA-seq analysis, Sci. Rep., 10(1): 1-10, 2020, doi:10.1038/s41598-020-64193-z
K. Kataoka, R. Minei, K. Ide, A. Ogura, H. Takeyama, M. Takeda, T. Suzuki,
K. Yura and T. Asahi, The Draft Genome Dataset of the Asian Cricket Teleogryllus
occipitalis for Molecular Research Toward Entomophagy, Front. Genet., 11:470, 2020, doi:10.3389/fgene.2020.00470
K. Tonouchi, Y. Adachi, S. Moriyama, K. Sano, K. Tabata, K. Ide, H. Takeyama, T. Suzuki and Y. Takahashi, Stereotyped B-cell response that counteracts antigenic variation of influenza viruses, Int. Immunol., 32(9): 613-621, 2020, doi:10.1093/intimm/dxaa038
A. Z. Samuel, R. Miyaoka, M. Ando, A. Gaebler, C. Thiele and H. Takeyama,
Molecular profiling of lipid droplets inside HuH7 cells with Raman micro-spectroscopy,
Commun. Biol., 3(1): 372, 2020, doi:10.1038/s42003-020-1100-4
T. Inagaki, S. Yamada, H. Fujii, T. Yoshikawa, M. Shibamura, S. Harada,
S. Fukushi, M. Q. Le, C. T. Nguyen, T. T. T. Nguyen, T. T. Nguyen, V. T.
Quach, V. D. Thong, K. Mori, M. Sasaki, A. Setiyono, E. Handharyani, H.
Takeyama, F. Hasebe and M. Saijo, Characterization of a Novel Alphaherpesvirus
Isolated from the Fruit Bat Pteropus lylei in Vietnam, J. Virol., 94(18), 2020, doi:10.1128/JVI.00673-20
D. Shiokawa, H. Sakai, H. Ohata, T. Miyazaki, Y. Kanda, S. Sekine, D. Narushima,
M. Hosokawa, M. Kato, Y. Suzuki, H. Takeyama, H. Kambara, H. Nakagama and
K. Okamoto, Slow-Cycling Cancer Stem Cells Regulate Progression and Chemoresistance
in Colon Cancer, Cancer Res., 80(20):4451-4464, 2020, doi:10.1158/0008-5472.CAN-20-0378
M. W. Lewaru, Y. Nishikawa, K. Ide, M. Kogawa, M. Hosokawa, A. Z. Samuel,
S. Sumimoto, H. Nuryadi, S. Suda and H. Takeyama, Draft Genome Sequence
of Okeania sp. Strain KiyG1, Assembled from Single-Amplified Genomes Collected
from Cape Kiyan, Okinawa, Japan, Microbiol. Resour. Announc., 9(46), 2020
K. Ide, Y. Nishikawa, M. Kogawa, E. Iwamoto, A. Z. Samuel, Y. Nakano and
H. Takeyama, High-Quality Draft Genome Sequence of a Rickettsiales Bacterium
Found in Acropora tenuis Coral from Okinawa, Japan, Microbiol. Resour. Announc., 9(48), 2020, doi:10.1128/MRA.00848-20
A. Z. Samuel, R. Mukojima, S. Horii, M. Ando, S. Egashira, T. Nakashima, M. Iwatsuki and H. Takeyama, On Selecting a Suitable Spectral Matching Method for Automated Analytical Applications of Raman Spectroscopy, ACS Omega, in press, 2021, doi:10.1021/acsomega.0c05041
Takikawa M., Fujisawa M., Yoshino K., Takeoka S., Intracellular Distribution
of Lipids and Encapsulated Model Drugs from Cationic Liposomes with Different
Uptake Pathways, Int. J. Nanomedicine. 2020;15:8401-8409.
Hu R., Sou K., Takeoka S., A rapid and highly sensitive biomarker detection
platform based on a temperature-responsive liposome-linked immunosorbent
assay, Sci. Rep. 2020, 10, 18086. DOI: 10.1038/s41598-020-75011-x
Riva E.R., Sinibaldi E., Grillone A.F., Del Turco S., Mondini A., Li T., Takeoka S., Mattoli V., Enhanced In Vitro Magnetic Cell Targeting of Doxorubicin-Loaded Magnetic Liposomes for Localized Cancer Therapy, Nanomaterials (Basel). 2020;10(11) 2104. Doi: 10.3390/nano10112104
M. Ogawa, N. Takada, S. Shizukuishi, M. Tomokiyo, B. Chang, M. Yoshida,
S. Kakuta, I. Tanida, A. Ryo, J. L. Guan, H. Takeyama and M. Ohnishi, Streptococcus
pneumoniae triggers hierarchical autophagy through reprogramming of LAPosome-like
vesicles via NDP52-delocalization, Commun. Biol., 3(1): 1-15, 2020, doi:10.1038/s42003-020-0753-3
H. Tsuyuzaki, M. Hosokawa, K. Arikawa, T. Yoda, N. Okada, H. Takeyama and
M. Sato, Time-lapse single-cell transcriptomics reveals modulation of histone
H3 for dormancy breaking in fission yeast, Nat. Commun., 11(1): 1265, 2020, doi:10.1038/s41467-020-15060-y
Sarker S.R., Takikawa M., Takeoka S., In Vitro Delivery of Cell Impermeable
Phallotoxin Using Cationic Liposomes Composed of Lipids Bearing Lysine
Headgroup, ACS Appl. Bio Mater. 2020, 3, 4, 2048–2057. DOI: 10.1021/acsabm.9b01167
2019
Li T, Zehner M, He J, Prochnicki T, Horvath G, Latz E, Burgdorf S, Takeoka S. NLRP3 inflammasome-activating arginine-based liposomes promote antigen presentations in dendritic cells. Int J Nanomedicine. 14:3503-3516, 2019.
He J, Li T, Prochnicki T, Horvath G, Latz E, Takeoka S. Membrane fusogenic lysine type lipid assemblies possess enhanced NLRP3
inflammasome activation potency. Biochem Biophys Rep. 18:100623, 2019
Nagata N, Tohya M, Fukuda S, Suda W, Nishijima S, Takeuchi F, Ohsugi M,
Tsujimoto T, Nakamura T, Shimomura A, Yanagisawa N, Hisada Y, Watanabe
K, Imbe K, Akiyama J, Mizokami M, Miyoshi-Akiyama T, Uemura N, Hattori M. Effects of bowel preparation on the human gut microbiome and metabolome.
Sci Rep. 9. 4042
Kondo S, Takahashi K, Kinoshita Y, Nagai J, Wakatsuki S, Araki T, Goshima Y, Ohshima T. Genetic inhibition of CRMP2 phosphorylation at serine 522 promotes axonal
regeneration after optic nerve injury. Sci Rep 9, 7188, 2019
Terahara K, Iwabuchi R, Hosokawa M, Nishikawa Y, Takeyama H, Takahashi Y, Tsunetsugu-Yokota Y. A CCR5+ memory subset within HIV-1-infected primary resting CD4+ T cells is permissive for replication-competent, latently infected viruses in vitro.
BMC Res Notes. 2019 Apr 29;12(1):242.
Matsumura T, Ikebe T, Arikawa K, Hosokawa M, Aiko M, Iguchi A, Togashi I, Kai S, Ohara S, Ohara N, Ohnishi M, Watanabe H, Kobayashi K, Takeyama H, Yamasaki S, Takahashi Y, Ato M. Sequential Sensing by TLR2 and Mincle Directs Immature Myeloid Cells to Protect against Invasive Group A Streptococcal Infection in Mice.
Cell Rep. 2019 Apr 9;27(2):561-571.e6.
Membrane fusogenic lysine type lipid assemblies possess enhanced NLRP3
inflammasome activation potency Jieyan He, Tianshu Li, Tomasz Próchnicki, Gabor Horvath, Eicke Latz, Shinji Takeoka. Biochemistry and Biophysics Reports, Volume 18, July 2019, 100623
Tanoue T, Morita S, Damian R. Plichta DR, Skelly AN, Suda W, Sugiura Y,
Seiko Narushima S, Vlamakis H, Motoo I, Sugita K, Shiota A, Takeshita K,
Yasuma K, Riethmacher D, Kaisho T, Norman JM, Mucida D, Suematsu M, Yaguchi
T, Bucci1 V, Inoue T, Kawakami Y, Olle B, Roberts B, Hattori M, Xavier RJ, Atarashi K, Honda K: A defined commensal consortium induces
CD8 T cells and anti-cancer immunity. Nature 565, 600-608 (2019).
Nakamoto N, Sasaki N, Aoki R, Miyamoto K, Suda W, Teratani T, Suzuki T,
Koda Y, Chu PS, Taniki N, Yamaguchi A, Kanamori M, Kamada N, Hattori M, Ashida H, Sakamoto M, Atarashi K, Narushima S, Yoshimura A, Honda K,
Sato T, Kanai T: Gut pathobionts underlie intestinal barrier dysfunction
and liver T helper 17 cell immune response in primary sclerosing cholangitis.
Nat Microbiol. Jan 14, 2019
Saito S, Sano K, Ainai A, Taga Y, Ueno T, Tabata K, Saito K, Wada Y, Ohara
Y, Takeyama H, Odagiri T, Kageyama T, Ogawa-Goto K, Multihartina P, Setiawaty V, Pangesti KNA, Hasegawa H. IgA tetramerization improves target breadth but not peak potency of functionality of anti-influenza virus broadly neutralizing antibody., PLOS Pathogens, 15(1):e1007427–23, 2019
Togashi K, Hasegawa M, Nagai J, Tonouchi A, Masukawa D, Hensley K, Goshima
Y, Ohshima T. Genetic suppression of CRMP2 phosphorylation improves outcome in MPTP-induced
Parkinson’s model mice. Genes Cells 24, 31-40, 2019
Yokota SI, Nakamura K, Ando M, Haraguchi A, Omori K, Shibata S. A low-protein diet eliminates the circadian rhythm of serum insulin and
hepatic lipid metabolism in mice. J Nutr Biochem. 63:177-185, 2019.
2018
Chiou TY, Suda W, Oshima K, Hattori M, Matsuzaki C, Yamamoto K, Takahashi T: Draft Genome Sequence of Lactobacillus kosoi NBRC 113063, Isolated from Kôso, a Japanese Sugar-Vegetable Fermented Beverage. Microbiol Resour Announc. 21;7(20), 2018
Kaito S, Toya T, Yoshifuji K, Kurosawa S, Inamoto K, Takeshita K, Suda
W, Kakihana K, Honda K, Hattori M, Ohashi K: Fecal microbiota transplantation with frozen capsules for a
patient with refractory acute gut graft-versus-host disease. Blood Adv. 2(22):3097-3101, 2018
Shimizu K, Kimura K, Isowa Y, Oshima K, Ishikawa M, Kagi H, Kito K, Hattori M, Chiba S, Endo K: Insights into the evolution of shells and love darts
of land snails revealed from their matrix proteins. Genome Biol Evol. Nov 2, 2018
Nakade Y, Iwata Y, Furuichi K, Mita M, Hamase K, Konno R, Miyake T, Sakai
N, Kitajima S, Toyama T, Shinozaki Y, Sagara A, Miyagawa T, Hara A, Shimizu
M, Kamikawa Y, Sato K, Oshima M, Yoneda-Nakagawa S, Yamamura Y, Kaneko
S, Miyamoto T, Katane M, Homma H, Morita H, Suda W, Hattori M, Wada T: Gut microbiota-derived D-serine protects against acute kidney injury. JCI Insight. 3: e97957, 2018
Kurokawa S, Kishimoto T, Mizuno S, Masaoka T, Naganuma M, Liang KC, Kitazawa
M, Nakashima M, Shindo C, Suda W, Hattori M, Kanai T, Mimura M: The effect of fecal microbiota transplantation on
psychiatric symptoms among patients with irritable bowel syndrome, functional
diarrhea and functional constipation: An open-label observational study.
J Affect Disord. 235: 506-512, 2018
Stein RR, Tanoue T, Szabady RL, Bhattarai SK, Olle B, Norman JM, Suda W, Oshima K, Hattori M, Gerber GK, Sander C, Honda K, Bucci V: Computer-guided design of optimal
microbial consortia for immune system modulation. Elife. 17;7. pii: e30916, 2018
Iwasawa K, Suda W, Tsunoda T, Oikawa-Kawamoto M, Umetsu S, Takayasu L,
Inui A, Fujisawa T, Morita H, Sogo T, Hattori M: Dysbiosis of the salivary microbiota in pediatric-onset primary sclerosing cholangitis and its potential as a biomarker. Sci Rep. 8(1): 5480, 2018
Nanki K, Mizuno S, Matsuoka K, Ono K, Sugimoto S, Kiyohara H, Arai M, Nakashima
M, Takeshita K, Saigusa K, Senoh M, Fukuda T, Naganuma M, Kato H, Suda
W, Hattori M, Kanai T: Fecal microbiota transplantation for recurrent Clostridium difficile infection in a patient with ulcerative colitis. Intest. Res. 16: 142-146, 2018
Kumagai Y, Yoshizawa S, Nakajima Y, Watanabe M, Fukunaga T, Ogura Y, Hayashi T, Oshima K, Hattori M, Ikeuchi M, Kogure K, DeLong EF, Iwasaki W: Solar-panel and parasol strategies
shape the proteorhodopsin distribution pattern in marine Flavobacteriia.
ISME J. 12(5): 1329-1343, 2018
Chiou TY, Suda W, Oshima K, Hattori M, Matsuzaki C, Yamamoto K, Takahashi T: Lactobacillus kosoi sp. nov., a
fructophilic species isolated from kôso, a Japanese sugar-vegetable fermented
beverage. Antonie Van Leeuwenhoek 111(7): 1149-1156, 2018
Koizumi T, Hattori M, Nara K: Ectomycorrhizal fungal communities in alpine relict forests of
Pinus pumila on Mt. Norikura, Japan. Mycorrhiza 28(2):129-145, 2018
Costea PI, Hildebrand F, Manimozhiyan A, Bäckhed F, Blaser MJ, Bushman FD, de Vos WM, Ehrlich SD, Fraser CM, Hattori M, Huttenhower C, Jeffery IB, Knights D, Lewis JD, Ley RE, Ochman H, O'Toole
PW, Quince C, Relman DA, Shanahan F, Sunagawa S, Wang J, Weinstock GM,
Wu GD, Zeller G, Zhao L, Raes J, Knight R, Bork P: Enterotypes in the landscape
of gut microbial community composition. Nat Microbiol. 3: 8-16, 2018
Naganuma M, Sugimoto S, Mitsuyama K, Kobayashi T, Yoshimura N, Ohi H, Tanaka
S, Andoh A, Ohmiya N, Saigusa K, Yamamoto T, Morohoshi Y, Ichikawa H, Matsuoka
K, Hisamatsu T, Watanabe K, Mizuno S, Suda W, Hattori M, Fukuda S, Hirayama A, Abe T, Watanabe M, Hibi T, Suzuki Y, Kanai T: INDIGO Study Group: Efficacy of Indigo naturalis in a Multicenter Randomized Controlled Trial of Patients with Ulcerative Colitis. Gastroenterology 154(4): 935-947, 2018
Taniguchi H, Tanisawa K, Sun X, Kubo T, Hoshino Y, Hosokawa M, Takeyama H, Higuchi M. Effects of short-term endurance exercise on gut microbiota
in elderly men. Physiological reports, 6(23):e13935, 2018
Inagaki T, Satoh M, Fujii H, Yamada S, Shibamura M, Yoshikawa T, Harada S, Takeyama H, Saijo M. Acyclovir Sensitivity and Neurovirulence of Herpes Simplex Virus Type 1 with Amino Acid Substitutions in the Viral Thymidine Kinase Gene, Which Were Detected in the Patients with Intractable Herpes Simplex Encephalitis Previously Reported. Japanese journal of infectious diseases, 71(5):343-349, 2018
Ogawa M, Matsuda R, Takada N, Tomokiyo M, Yamamoto S, Shizukusihi S, Yamaji
T, Yoshikawa Y, Yoshida M, Tanida I, Koike M, Murai M, Morita H, Takeyama H, Ryo A, Guan JL, Yamamoto M, Inoue JI, Yanagawa T, Fukuda M, Kawabe H,
Ohnishi M, Molecular mechanisms of Streptococcus pneumoniae-targeted autophagy
via pneumolysin, Golgi-resident Rab41, and Nedd4-1-mediated K63-linked
ubiquitination. Cellular microbiology, 20(8):e12846, 2018
Motone K, Takagi T, Aburaya S, Aoki W, Miura N, Minakuchi H, Takeyama H, Nagasaki Y, Shinzato C, Ueda M, Protection of Coral Larvae from Thermally
Induced Oxidative Stress by Redox Nanoparticles. Marine biotechnology (New York, N.Y.), 20(4):542-548, 2018
Chung J, Wang X, Maruyama T, Ma Y, Zhang X, Mez J, Sherva R, Takeyama H, Alzheimer's Disease Neuroimaging Initiative., Lunetta KL, Farrer LA, Jun GR, Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages. Alzheimer's & dementia : the journal of the Alzheimer's Association, 14(5)623-633, 2018
Omura N, Yoshikawa T, Fujii H, Shibamura M, Inagaki T, Kato H, Egawa K,
Harada S, Yamada S, Takeyama H, Saijo M, A Novel System for Constructing a Recombinant Highly-Attenuated
Vaccinia Virus Strain (LC16m8) Expressing Foreign Genes and Its Application
for the Generation of LC16m8-Based Vaccines against Herpes Simplex Virus
2. Japanese journal of infectious diseases, 71(3):229-233, 2018
Iwabuchi R, Ikeno S, Kobayashi-Ishihara M, Takeyama H, Ato M, Tsunetsugu-Yokota Y, Terahara K. Introduction of Human Flt3-L
and GM-CSF into Humanized Mice Enhances the Reconstitution and Maturation
of Myeloid Dendritic Cells and the Development of Foxp3+CD4+ T Cells.,
Front. Immunol., 9:1042, 2018
Nakamura H, Takahashi-Jitsuki A, Makihara H, Asano T, Kimura Y, Nakabayashi
J, Yamashita N, Nakamura F, Ohshima T, Hirano H, Tanaka F, Goshima Y. Proteome and behavioral alternations in
knock-in mice expressing nonphosphorylated CRMP2S522A. Neurochem Int. 119:207-217, 2018
Ueda Y, Shimizu Y, Ishitani T, Ohshima T. Involvement of Shh and Notch signalings in regenerative neurogenesis
in adult zebrafish optic tectum after stab injury. J Comp Neurol 526, 2360-2372, 2018
Chiang M-C, Huang A.J.Y., Wintzer M.E., Ohshima T, McHugh T. J. A role for CA3 in social recognition memory. Behavioral Brain Res 354, 22-30, 2018
Shimizu Y, Ueda Y, Ohshima T. Wnt signaling regulates proliferation and differentiation of radial glia
in regenerative processes after stab injury in the optic tectum of adult
zebrafish. Glia 66:1382-1394, 2018
Kamiki E, Boehringer R, Polygalov D, Ohshima T, McHugh T. Inducible knockout of the Cyclin-dependent kinase 5 activator
p35 alters hippocampal spatial coding and neuronal excitability. Frontiers in Cellular Neuroscience 12, 138, 2018
Komada Y, Ikeda Y, Sato M, Kami A, Masuda C, Shibata S. Social jetlag and menstrual symptoms among female university students. Chronobiol Int. 5:1-7, 2018
Aoyama S, Kojima S, Sasaki K, Ishikawa R, Tanaka M, Shimoda T, Hattori
Y, Aoki N, Takahashi K, Hirooka R, Takizawa M, Haraguchi A, Shibata S. Day-Night Oscillation of Atrogin1 and Timing-Dependent Preventive Effect
of Weight-Bearing on Muscle Atrophy. EBioMedicine. 37:499-508, 2018
Whittaker DS, Loh DH, Wang HB, Tahara Y, Kuljis D, Cutler T, Ghiani CA, Shibata S, Block GD, Colwell CS. Circadian-based Treatment Strategy Effective in
the BACHD Mouse Model of Huntington's Disease. J Biol Rhythms. 33(5):535-554, 2018
Takahashi M, Tahara Y, Tsubosaka M, Fukazawa M, Ozaki M, Iwakami T, Nakaoka T, Shibata S. Chronotype and social jetlag influence human circadian clock gene expression.
Sci Rep. 5;8(1):10152, 2018
Fukuda T, Haraguchi A, Takahashi M, Nakaoka T, Fukazawa M, Okubo J, Ozaki
M, Kanatome A, Ohya R, Miura Y, Obara K, Shibata S. A randomized, double-blind and placebo-controlled crossover trial on
the effect of l-ornithine ingestion on the human circadian clock. Chronobiol Int. 35(10):1445-1455, 2018.
Tsurudome Y, Koyanagi S, Kanemitsu T, Katamune C, Oda M, Kanado Y, Kato M, Morita A, Tahara Y, Matsunaga N, Shibata S, Ohdo S. Circadian clock component PERIOD2 regulates diurnal expression
of Na+/H+ exchanger regulatory factor-1 and its scaffolding function. Sci Rep. 8(1):9072, 2018
Li T, He J, Horvath G, Prochnicki T, Latz E, Takeoka S. Lysine-containing cationic liposomes activate the NLRP3 inflammasome:
effect of a spacer between the head group and the hydrophobic moieties
of the lipids. Nanomedicine 14(2):279-288, 2018
Sarker SR, Takeoka S. Amino acid-based liposomal assemblies: Intracellular plasmid DNA delivery nanoparticles. J Nanomedicine. 2:1008, 2018