Publication

2020

Sugeno A, Piao W, Yamazaki M, Takahashi K, Arikawa K, Matsunaga H, Hosokawa M, Tominaga D, Goshima Y, Takeyama H, Ohshima T. Cortical transcriptome analysis after spinal cord injury reveals new insights on the regeneration mechanism of CNS upon inhibition of CRMP2 phosphorylation. Neural Regeneration Research 16(7):1258-1265. DOI: 10.4103/1673-5374.301035

Togashi K, Hasegawa M, Nagai J, Kotaka K, Yazawa A, Takahashi M, Masukawa D, Goshima Y, Hensley K, Ohshima T. Lanthionine ketimine ester improves outcome in an MPTP-induced mouse model of Parkinson’s disease via suppressions of CRMP2 phosphorylation and microglial activation. J Neurol Sci 413:116802. DOI: 10.1016/j.jns.2020.116802

O. Schanz, R. Chijiiwa, S. C. Cengiz, Y. Majlesain, H. Weighardt, H. Takeyama and I. Förster, Dietary AhR Ligands Regulate AhRR Expression in Intestinal Immune Cells and Intestinal Microbiota Composition, Int. J. Mol. Sci, 21(9):3189, 2020, doi:10.3390/ijms21093189

M. Yamazaki, M. Hosokawa, K. Arikawa, K. Takahashi, C. Sakanashi, T. Yoda, H. Matsunaga and H. Takeyama, Effective microtissue RNA extraction coupled with Smart-seq2 for reproducible and robust spatial transcriptome analysis, Sci. Rep., 10(1): 1-8, 2020, doi:10.1038/s41598-020-63495-6

M. Yumoto, N. Hemmi, N. Sato, Y. Kawashima, K. Arikawa, K. Ide, M. Hosokawa, M. Seo and H. Takeyama, Evaluation of the effects of cell-dispensing using an inkjet-based bioprinter on cell integrity by RNA-seq analysis, Sci. Rep., 10(1): 1-10, 2020, doi:10.1038/s41598-020-64193-z

K. Kataoka, R. Minei, K. Ide, A. Ogura, H. Takeyama, M. Takeda, T. Suzuki, K. Yura and T. Asahi, The Draft Genome Dataset of the Asian Cricket Teleogryllus occipitalis for Molecular Research Toward Entomophagy, Front. Genet., 11:470, 2020, doi:10.3389/fgene.2020.00470

K. Tonouchi, Y. Adachi, S. Moriyama, K. Sano, K. Tabata, K. Ide, H. Takeyama, T. Suzuki and Y. Takahashi, Stereotyped B-cell response that counteracts antigenic variation of influenza viruses, Int. Immunol., 32(9): 613-621, 2020, doi:10.1093/intimm/dxaa038

A. Z. Samuel, R. Miyaoka, M. Ando, A. Gaebler, C. Thiele and H. Takeyama, Molecular profiling of lipid droplets inside HuH7 cells with Raman micro-spectroscopy, Commun. Biol., 3(1): 372, 2020, doi:10.1038/s42003-020-1100-4

T. Inagaki, S. Yamada, H. Fujii, T. Yoshikawa, M. Shibamura, S. Harada, S. Fukushi, M. Q. Le, C. T. Nguyen, T. T. T. Nguyen, T. T. Nguyen, V. T. Quach, V. D. Thong, K. Mori, M. Sasaki, A. Setiyono, E. Handharyani, H. Takeyama, F. Hasebe and M. Saijo, Characterization of a Novel Alphaherpesvirus Isolated from the Fruit Bat Pteropus lylei in Vietnam, J. Virol., 94(18), 2020, doi:10.1128/JVI.00673-20

D. Shiokawa, H. Sakai, H. Ohata, T. Miyazaki, Y. Kanda, S. Sekine, D. Narushima, M. Hosokawa, M. Kato, Y. Suzuki, H. Takeyama, H. Kambara, H. Nakagama and K. Okamoto, Slow-Cycling Cancer Stem Cells Regulate Progression and Chemoresistance in Colon Cancer, Cancer Res., 80(20):4451-4464, 2020, doi:10.1158/0008-5472.CAN-20-0378

M. W. Lewaru, Y. Nishikawa, K. Ide, M. Kogawa, M. Hosokawa, A. Z. Samuel, S. Sumimoto, H. Nuryadi, S. Suda and H. Takeyama, Draft Genome Sequence of Okeania sp. Strain KiyG1, Assembled from Single-Amplified Genomes Collected from Cape Kiyan, Okinawa, Japan, Microbiol. Resour. Announc., 9(46), 2020

K. Ide, Y. Nishikawa, M. Kogawa, E. Iwamoto, A. Z. Samuel, Y. Nakano and H. Takeyama, High-Quality Draft Genome Sequence of a Rickettsiales Bacterium Found in Acropora tenuis Coral from Okinawa, Japan, Microbiol. Resour. Announc., 9(48), 2020, doi:10.1128/MRA.00848-20

A. Z. Samuel, R. Mukojima, S. Horii, M. Ando, S. Egashira, T. Nakashima, M. Iwatsuki and H. Takeyama, On Selecting a Suitable Spectral Matching Method for Automated Analytical Applications of Raman Spectroscopy, ACS Omega, in press, 2021, doi:10.1021/acsomega.0c05041

Takikawa M., Fujisawa M., Yoshino K., Takeoka S., Intracellular Distribution of Lipids and Encapsulated Model Drugs from Cationic Liposomes with Different Uptake Pathways, Int. J. Nanomedicine. 2020;15:8401-8409.

Hu R., Sou K., Takeoka S., A rapid and highly sensitive biomarker detection platform based on a temperature-responsive liposome-linked immunosorbent assay, Sci. Rep. 2020, 10, 18086. DOI: 10.1038/s41598-020-75011-x

Riva E.R., Sinibaldi E., Grillone A.F., Del Turco S., Mondini A., Li T., Takeoka S., Mattoli V., Enhanced In Vitro Magnetic Cell Targeting of Doxorubicin-Loaded Magnetic Liposomes for Localized Cancer Therapy, Nanomaterials (Basel). 2020;10(11) 2104. Doi: 10.3390/nano10112104

M. Ogawa, N. Takada, S. Shizukuishi, M. Tomokiyo, B. Chang, M. Yoshida, S. Kakuta, I. Tanida, A. Ryo, J. L. Guan, H. Takeyama and M. Ohnishi, Streptococcus pneumoniae triggers hierarchical autophagy through reprogramming of LAPosome-like vesicles via NDP52-delocalization, Commun. Biol., 3(1): 1-15, 2020, doi:10.1038/s42003-020-0753-3

H. Tsuyuzaki, M. Hosokawa, K. Arikawa, T. Yoda, N. Okada, H. Takeyama and M. Sato, Time-lapse single-cell transcriptomics reveals modulation of histone H3 for dormancy breaking in fission yeast, Nat. Commun., 11(1): 1265, 2020, doi:10.1038/s41467-020-15060-y

Sarker S.R., Takikawa M., Takeoka S., In Vitro Delivery of Cell Impermeable Phallotoxin Using Cationic Liposomes Composed of Lipids Bearing Lysine Headgroup, ACS Appl. Bio Mater. 2020, 3, 4, 2048–2057. DOI: 10.1021/acsabm.9b01167

2019

Li T, Zehner M, He J, Prochnicki T, Horvath G, Latz E, Burgdorf S, Takeoka S. NLRP3 inflammasome-activating arginine-based liposomes promote antigen presentations in dendritic cells. Int J Nanomedicine. 14:3503-3516, 2019.

He J, Li T, Prochnicki T, Horvath G, Latz E, Takeoka S. Membrane fusogenic lysine type lipid assemblies possess enhanced NLRP3 inflammasome activation potency. Biochem Biophys Rep. 18:100623, 2019

Nagata N, Tohya M, Fukuda S, Suda W, Nishijima S, Takeuchi F, Ohsugi M, Tsujimoto T, Nakamura T, Shimomura A, Yanagisawa N, Hisada Y, Watanabe K, Imbe K, Akiyama J, Mizokami M, Miyoshi-Akiyama T, Uemura N, Hattori M. Effects of bowel preparation on the human gut microbiome and metabolome. Sci Rep. 9. 4042

Kondo S, Takahashi K, Kinoshita Y, Nagai J, Wakatsuki S, Araki T, Goshima Y, Ohshima T. Genetic inhibition of CRMP2 phosphorylation at serine 522 promotes axonal regeneration after optic nerve injury. Sci Rep 9, 7188, 2019

Terahara K, Iwabuchi R, Hosokawa M, Nishikawa Y, Takeyama H, Takahashi Y, Tsunetsugu-Yokota Y. A CCR5+ memory subset within HIV-1-infected primary resting CD4+ T cells is permissive for replication-competent, latently infected viruses in vitro.
BMC Res Notes. 2019 Apr 29;12(1):242.

Matsumura T, Ikebe T, Arikawa K, Hosokawa M, Aiko M, Iguchi A, Togashi I, Kai S, Ohara S, Ohara N, Ohnishi M, Watanabe H, Kobayashi K, Takeyama H, Yamasaki S, Takahashi Y, Ato M. Sequential Sensing by TLR2 and Mincle Directs Immature Myeloid Cells to Protect against Invasive Group A Streptococcal Infection in Mice.
Cell Rep. 2019 Apr 9;27(2):561-571.e6.

Membrane fusogenic lysine type lipid assemblies possess enhanced NLRP3 inflammasome activation potency Jieyan He, Tianshu Li, Tomasz Próchnicki, Gabor Horvath, Eicke Latz, Shinji Takeoka. Biochemistry and Biophysics Reports, Volume 18, July 2019, 100623

Tanoue T, Morita S, Damian R. Plichta DR, Skelly AN, Suda W, Sugiura Y, Seiko Narushima S, Vlamakis H, Motoo I, Sugita K, Shiota A, Takeshita K, Yasuma K, Riethmacher D, Kaisho T, Norman JM, Mucida D, Suematsu M, Yaguchi T, Bucci1 V, Inoue T, Kawakami Y, Olle B, Roberts B, Hattori M, Xavier RJ, Atarashi K, Honda K: A defined commensal consortium induces CD8 T cells and anti-cancer immunity. Nature 565, 600-608 (2019).

Nakamoto N, Sasaki N, Aoki R, Miyamoto K, Suda W, Teratani T, Suzuki T, Koda Y, Chu PS, Taniki N, Yamaguchi A, Kanamori M, Kamada N, Hattori M, Ashida H, Sakamoto M, Atarashi K, Narushima S, Yoshimura A, Honda K, Sato T, Kanai T: Gut pathobionts underlie intestinal barrier dysfunction and liver T helper 17 cell immune response in primary sclerosing cholangitis. Nat Microbiol. Jan 14, 2019

Saito S, Sano K, Ainai A, Taga Y, Ueno T, Tabata K, Saito K, Wada Y, Ohara Y, Takeyama H, Odagiri T, Kageyama T, Ogawa-Goto K, Multihartina P, Setiawaty V, Pangesti KNA, Hasegawa H. IgA tetramerization improves target breadth but not peak potency of functionality of anti-influenza virus broadly neutralizing antibody., PLOS Pathogens, 15(1):e1007427–23, 2019

Togashi K, Hasegawa M, Nagai J, Tonouchi A, Masukawa D, Hensley K, Goshima Y, Ohshima T. Genetic suppression of CRMP2 phosphorylation improves outcome in MPTP-induced Parkinson’s model mice. Genes Cells 24, 31-40, 2019

Yokota SI, Nakamura K, Ando M, Haraguchi A, Omori K, Shibata S. A low-protein diet eliminates the circadian rhythm of serum insulin and hepatic lipid metabolism in mice. J Nutr Biochem. 63:177-185, 2019.

2018

Chiou TY, Suda W, Oshima K, Hattori M, Matsuzaki C, Yamamoto K, Takahashi T: Draft Genome Sequence of Lactobacillus kosoi NBRC 113063, Isolated from Kôso, a Japanese Sugar-Vegetable Fermented Beverage. Microbiol Resour Announc. 21;7(20), 2018

Kaito S, Toya T, Yoshifuji K, Kurosawa S, Inamoto K, Takeshita K, Suda W, Kakihana K, Honda K, Hattori M, Ohashi K: Fecal microbiota transplantation with frozen capsules for a patient with refractory acute gut graft-versus-host disease. Blood Adv. 2(22):3097-3101, 2018

Shimizu K, Kimura K, Isowa Y, Oshima K, Ishikawa M, Kagi H, Kito K, Hattori M, Chiba S, Endo K: Insights into the evolution of shells and love darts of land snails revealed from their matrix proteins. Genome Biol Evol. Nov 2, 2018

Nakade Y, Iwata Y, Furuichi K, Mita M, Hamase K, Konno R, Miyake T, Sakai N, Kitajima S, Toyama T, Shinozaki Y, Sagara A, Miyagawa T, Hara A, Shimizu M, Kamikawa Y, Sato K, Oshima M, Yoneda-Nakagawa S, Yamamura Y, Kaneko S, Miyamoto T, Katane M, Homma H, Morita H, Suda W, Hattori M, Wada T: Gut microbiota-derived D-serine protects against acute kidney injury. JCI Insight. 3: e97957, 2018

Kurokawa S, Kishimoto T, Mizuno S, Masaoka T, Naganuma M, Liang KC, Kitazawa M, Nakashima M, Shindo C, Suda W, Hattori M, Kanai T, Mimura M: The effect of fecal microbiota transplantation on psychiatric symptoms among patients with irritable bowel syndrome, functional diarrhea and functional constipation: An open-label observational study. J Affect Disord. 235: 506-512, 2018

Stein RR, Tanoue T, Szabady RL, Bhattarai SK, Olle B, Norman JM, Suda W, Oshima K, Hattori M, Gerber GK, Sander C, Honda K, Bucci V: Computer-guided design of optimal microbial consortia for immune system modulation. Elife. 17;7. pii: e30916, 2018

Iwasawa K, Suda W, Tsunoda T, Oikawa-Kawamoto M, Umetsu S, Takayasu L, Inui A, Fujisawa T, Morita H, Sogo T, Hattori M: Dysbiosis of the salivary microbiota in pediatric-onset primary sclerosing cholangitis and its potential as a biomarker. Sci Rep. 8(1): 5480, 2018

Nanki K, Mizuno S, Matsuoka K, Ono K, Sugimoto S, Kiyohara H, Arai M, Nakashima M, Takeshita K, Saigusa K, Senoh M, Fukuda T, Naganuma M, Kato H, Suda W, Hattori M, Kanai T: Fecal microbiota transplantation for recurrent Clostridium difficile infection in a patient with ulcerative colitis. Intest. Res. 16: 142-146, 2018

Kumagai Y, Yoshizawa S, Nakajima Y, Watanabe M, Fukunaga T, Ogura Y, Hayashi T, Oshima K, Hattori M, Ikeuchi M, Kogure K, DeLong EF, Iwasaki W: Solar-panel and parasol strategies shape the proteorhodopsin distribution pattern in marine Flavobacteriia. ISME J. 12(5): 1329-1343, 2018

Chiou TY, Suda W, Oshima K, Hattori M, Matsuzaki C, Yamamoto K, Takahashi T: Lactobacillus kosoi sp. nov., a fructophilic species isolated from kôso, a Japanese sugar-vegetable fermented beverage. Antonie Van Leeuwenhoek 111(7): 1149-1156, 2018

Koizumi T, Hattori M, Nara K: Ectomycorrhizal fungal communities in alpine relict forests of Pinus pumila on Mt. Norikura, Japan. Mycorrhiza 28(2):129-145, 2018

Costea PI, Hildebrand F, Manimozhiyan A, Bäckhed F, Blaser MJ, Bushman FD, de Vos WM, Ehrlich SD, Fraser CM, Hattori M, Huttenhower C, Jeffery IB, Knights D, Lewis JD, Ley RE, Ochman H, O'Toole PW, Quince C, Relman DA, Shanahan F, Sunagawa S, Wang J, Weinstock GM, Wu GD, Zeller G, Zhao L, Raes J, Knight R, Bork P: Enterotypes in the landscape of gut microbial community composition. Nat Microbiol. 3: 8-16, 2018

Naganuma M, Sugimoto S, Mitsuyama K, Kobayashi T, Yoshimura N, Ohi H, Tanaka S, Andoh A, Ohmiya N, Saigusa K, Yamamoto T, Morohoshi Y, Ichikawa H, Matsuoka K, Hisamatsu T, Watanabe K, Mizuno S, Suda W, Hattori M, Fukuda S, Hirayama A, Abe T, Watanabe M, Hibi T, Suzuki Y, Kanai T: INDIGO Study Group: Efficacy of Indigo naturalis in a Multicenter Randomized Controlled Trial of Patients with Ulcerative Colitis. Gastroenterology 154(4): 935-947, 2018

Taniguchi H, Tanisawa K, Sun X, Kubo T, Hoshino Y, Hosokawa M, Takeyama H, Higuchi M. Effects of short-term endurance exercise on gut microbiota in elderly men. Physiological reports, 6(23):e13935, 2018

Inagaki T, Satoh M, Fujii H, Yamada S, Shibamura M, Yoshikawa T, Harada S, Takeyama H, Saijo M. Acyclovir Sensitivity and Neurovirulence of Herpes Simplex Virus Type 1 with Amino Acid Substitutions in the Viral Thymidine Kinase Gene, Which Were Detected in the Patients with Intractable Herpes Simplex Encephalitis Previously Reported. Japanese journal of infectious diseases, 71(5):343-349, 2018

Ogawa M, Matsuda R, Takada N, Tomokiyo M, Yamamoto S, Shizukusihi S, Yamaji T, Yoshikawa Y, Yoshida M, Tanida I, Koike M, Murai M, Morita H, Takeyama H, Ryo A, Guan JL, Yamamoto M, Inoue JI, Yanagawa T, Fukuda M, Kawabe H, Ohnishi M, Molecular mechanisms of Streptococcus pneumoniae-targeted autophagy via pneumolysin, Golgi-resident Rab41, and Nedd4-1-mediated K63-linked ubiquitination. Cellular microbiology, 20(8):e12846, 2018

Motone K, Takagi T, Aburaya S, Aoki W, Miura N, Minakuchi H, Takeyama H, Nagasaki Y, Shinzato C, Ueda M, Protection of Coral Larvae from Thermally Induced Oxidative Stress by Redox Nanoparticles. Marine biotechnology (New York, N.Y.), 20(4):542-548, 2018

Chung J, Wang X, Maruyama T, Ma Y, Zhang X, Mez J, Sherva R, Takeyama H, Alzheimer's Disease Neuroimaging Initiative., Lunetta KL, Farrer LA, Jun GR, Genome-wide association study of Alzheimer's disease endophenotypes at prediagnosis stages. Alzheimer's & dementia : the journal of the Alzheimer's Association, 14(5)623-633, 2018

Omura N, Yoshikawa T, Fujii H, Shibamura M, Inagaki T, Kato H, Egawa K, Harada S, Yamada S, Takeyama H, Saijo M, A Novel System for Constructing a Recombinant Highly-Attenuated Vaccinia Virus Strain (LC16m8) Expressing Foreign Genes and Its Application for the Generation of LC16m8-Based Vaccines against Herpes Simplex Virus 2. Japanese journal of infectious diseases, 71(3):229-233, 2018

Iwabuchi R, Ikeno S, Kobayashi-Ishihara M, Takeyama H, Ato M, Tsunetsugu-Yokota Y, Terahara K. Introduction of Human Flt3-L and GM-CSF into Humanized Mice Enhances the Reconstitution and Maturation of Myeloid Dendritic Cells and the Development of Foxp3+CD4+ T Cells., Front. Immunol., 9:1042, 2018

Nakamura H, Takahashi-Jitsuki A, Makihara H, Asano T, Kimura Y, Nakabayashi J, Yamashita N, Nakamura F, Ohshima T, Hirano H, Tanaka F, Goshima Y. Proteome and behavioral alternations in knock-in mice expressing nonphosphorylated CRMP2S522A. Neurochem Int. 119:207-217, 2018

Ueda Y, Shimizu Y, Ishitani T, Ohshima T. Involvement of Shh and Notch signalings in regenerative neurogenesis in adult zebrafish optic tectum after stab injury. J Comp Neurol 526, 2360-2372, 2018

Chiang M-C, Huang A.J.Y., Wintzer M.E., Ohshima T, McHugh T. J. A role for CA3 in social recognition memory. Behavioral Brain Res 354, 22-30, 2018

Shimizu Y, Ueda Y, Ohshima T. Wnt signaling regulates proliferation and differentiation of radial glia in regenerative processes after stab injury in the optic tectum of adult zebrafish. Glia 66:1382-1394, 2018

Kamiki E, Boehringer R, Polygalov D, Ohshima T, McHugh T. Inducible knockout of the Cyclin-dependent kinase 5 activator p35 alters hippocampal spatial coding and neuronal excitability. Frontiers in Cellular Neuroscience 12, 138, 2018

Komada Y, Ikeda Y, Sato M, Kami A, Masuda C, Shibata S. Social jetlag and menstrual symptoms among female university students. Chronobiol Int. 5:1-7, 2018

Aoyama S, Kojima S, Sasaki K, Ishikawa R, Tanaka M, Shimoda T, Hattori Y, Aoki N, Takahashi K, Hirooka R, Takizawa M, Haraguchi A, Shibata S. Day-Night Oscillation of Atrogin1 and Timing-Dependent Preventive Effect of Weight-Bearing on Muscle Atrophy. EBioMedicine. 37:499-508, 2018

Whittaker DS, Loh DH, Wang HB, Tahara Y, Kuljis D, Cutler T, Ghiani CA, Shibata S, Block GD, Colwell CS. Circadian-based Treatment Strategy Effective in the BACHD Mouse Model of Huntington's Disease. J Biol Rhythms. 33(5):535-554, 2018

Takahashi M, Tahara Y, Tsubosaka M, Fukazawa M, Ozaki M, Iwakami T, Nakaoka T, Shibata S. Chronotype and social jetlag influence human circadian clock gene expression. Sci Rep. 5;8(1):10152, 2018

Fukuda T, Haraguchi A, Takahashi M, Nakaoka T, Fukazawa M, Okubo J, Ozaki M, Kanatome A, Ohya R, Miura Y, Obara K, Shibata S. A randomized, double-blind and placebo-controlled crossover trial on the effect of l-ornithine ingestion on the human circadian clock. Chronobiol Int. 35(10):1445-1455, 2018.

Tsurudome Y, Koyanagi S, Kanemitsu T, Katamune C, Oda M, Kanado Y, Kato M, Morita A, Tahara Y, Matsunaga N, Shibata S, Ohdo S. Circadian clock component PERIOD2 regulates diurnal expression of Na+/H+ exchanger regulatory factor-1 and its scaffolding function. Sci Rep. 8(1):9072, 2018

Li T, He J, Horvath G, Prochnicki T, Latz E, Takeoka S. Lysine-containing cationic liposomes activate the NLRP3 inflammasome: effect of a spacer between the head group and the hydrophobic moieties of the lipids. Nanomedicine 14(2):279-288, 2018

Sarker SR, Takeoka S. Amino acid-based liposomal assemblies: Intracellular plasmid DNA delivery nanoparticles. J Nanomedicine. 2:1008, 2018