Shigenobu Shibata

Official Title

Professor
Department of Electrical Engineering and Bioscience
Faculty of Science and Engineering

Examples of Classes Taught

Current topics in Bioscience

Research Fields

Chronobiology、Chrono-nutrition、Health Sciences

Research

Basic and applied studies of biological rhythms for health science and industry
　We have biological clock systems operated for chronological timing of our body. Now abnormality of clock system is known to cause various mental diseases such as developmental problem, insomnia/depression, and also metabolic diseases such as obesity, hypercholesteremia and alcoholism, and cancer disease. In order to promote good health, we studied basic and applied sciences of biological clock system based on chronobiology, chrono-pharmacology, chrono-nutrition and chrono-exercise using animals and humans. We will find the functional foods and nutrients, and various exercises such as running and swimming for maintaining healthy circadian rhythm. Finally we proposed the good recipe depending on chrono-nutrition and chrono-exercise for good health and for industrial products.

Selected publications

1. Kaur S, Teoh AN, Shukri NHM, Shafie SR, Bustami NA, Takahashi M, Lim PJ, Shibata S. Circadian rhythm and its association with birth and infant outcomes: research protocol of a prospective cohort study. BMC Pregnancy Childbirth. 20(1):96. 2020 2. Orihara K, Haraguchi A, Shibata S. Crosstalk Among Circadian Rhythm, Obesity and Allergy. Int J Mol Sci. 21(5):1884.2020 3. Aoyama S, Shibata S.Time-of-Day-Dependent Physiological Responses to Meal and Exercise. Front Nutr. 7:18. 2020 4. Kim HK, Chijiki H, Nanba T, Ozaki M, Sasaki H, Takahashi M, Shibata S. Ingestion of Helianthus tuberosus at Breakfast Rather Than at Dinner Is More Effective for Suppressing Glucose Levels and Improving the Intestinal Microbiota in Older Adults. Nutrients. 12(10):3035.2020 5. Motohashi H, Tahara Y, Whittaker DS, Wang HB, Yamaji T, Wakui H, Haraguchi A, Yamazaki M, Miyakawa H, Hama K, Sasaki H, Sakai T, Hirooka R, Takahashi K, Takizawa M, Makino S, Aoyama S, Colwell CS, Shibata S.The circadian clock is disrupted in mice with adenine-induced tubulointerstitial nephropathy. Kidney Int. 97(4):728-740. 2020 6. Tateishi N, Morita S, Yamazaki I, Okumura H, Kominami M, Akazawa S, Funaki A, Tomimori N, Rogi T, Shibata H, Shibata S. Administration timing and duration-dependent effects of sesamin isomers on lipid metabolism in rats. Chronobiol Int. 37(4):493-509. 2020 7. Akter S, Uddin KR, Sasaki H, Lyu Y, Shibata S.Gamma oryzanol impairs alcohol-induced anxiety-like behavior in mice via upregulation of central monoamines associated with Bdnf and Il-1β signaling. Sci Rep. 10(1):10677. 2020

研究室のHPアドレス

Home Page: https://www.waseda-shibatas.com/